Database
Compare
Undulatory Locomotion
TransmissionsAbility to propagate flexural waves along the length of the worm allows an increase in speed and range outside host, increasing infectiousness

Unholy Engineer
GenesHarder for drones to target lairs
Unique Abilities
AbilitiesUnique Abilities are abilities that are special to a certain plague type.

Unknown Origin
AchievementsScore 3 biohazards with Unknown Origin scenario

Unknown Origin
ScenariosEveryone has a favourite country, unfortunately you don't get to choose it here… Are you feeling lucky?

Unlock Annihilate gene
AbilitiesUnleash armageddon on the world!

Unlock Cheatmodes
AchievementsUnlock the cheats by winning a game on Normal for ALL disease types

Unscheduled Flight
AbilitiesUnlock an Active Ability that lets you send an infected person to a country of your choice

Unstable trajectory
GenesMore meteors but they strike continent randomly

Uphill Ice Skating
AchievementsDiscover the Uphill Ice Skating Combo
Urban Countries
MechanicsUrban countries are a type of country where the majority of the population lives in cities. Infection in Urban Areas spreads faster due to the high population density of the environment. This makes Rodent transmissions more effective in these countries. The following are a list of them:

Urbophile
GenesGive your plague a bonus in urban environments

Urogenital Expansion
TransmissionsVirus can replicate in kidneys and urinary tract, increasing infectiousness through urine and other bodily fluids

USA
CountriesA rich, urban country. Typically has a balanced climate

Use your head
AchievementsDiscover the Cranial Dispersion combo
Vaccine Shield
MechanicsPathogen introduces key genetic variations that renders the smallpox vaccine ineffective
Vampire
PathogensVampires are protagonist entities in the Shadow Plague.

Vampire Bat
SymptomsBats have become addicted to human blood - increasing the frequency and severity of their attacks. Attacks also alert nearby zombies to the presence of humans

Vampire Master
AchievementsBeat Shadow Plague on mega-brutal difficulty

Vampiric Awakening
SymptomsCreate a new vampire by temporarily producing toxic mutagens. Almost all Infected will die but eventually, a viable host will be found (Reusable).

Vampiric Hunger
SymptomsZombie prefers to suck the blood from the prey rather than eat the flesh. Prey more likely to remain intact and become a zombie

Van Helsing's Doom
AchievementsDestroy a Templar fort

Viral Affinity
GenesIncreases ape to ape transmission

Viral Instability 1
MechanicsDNA becomes unstable, increasing random mutations