Pathogens
CompareStonehenge
Stonehenge is an origin story exclusive to the Shadow Plague DLC.
Templar Bases
Templar Bases are enemy structures in Plague Inc.

Templars
When the Templars fully reveal themselves, they will have fortified anywhere from four to seven countries, unlike Z Com, who only fortify one country initially. The Templars will fortify countries with the least amount of infected humans, or at random if there are none. Similar to Z Com, the Templars can create additional bases by sending reinforcement planes.

Trematoda
Trematoda is a parasite-type plague available in Plague Inc: Evolved and Plague Inc. Mobile for the beta of the 2025 Update. it was inspired by real-world flatworms, also commonly called flukes, the Trematoda introduces a highly specialized lifecycle that relies on multiple hosts, environmental persistence, and stealthy progression. Unlike viral or bacterial plagues, Trematoda must carefully balance survival in intermediate hosts with slow but inevitable adaptation to humans.
Vampire
Vampires are protagonist entities in the Shadow Plague.

Virus
A rapidly mutating pathogen which is extremely hard to control
WHO laboratories
WHO research labs, as identified in-game, are considered to be the Shadow Plague equivalent of Gen-Sys labs. The labs have a flask on the roof but if attacked, the flask will have a red X over it after a few seconds being attacked by sending vampires to the lab or by filling the country with Shadow Slaves. A slash in cure research will increase the time to cure the plague. A popup will appear with a destroyed lab. They are relatively easy to destroy, similar to those in the Simian Flu. However, unlike the Simian Flu, if the player evolves…

Xenolith
Ancient and utterly alien crystal. Transforms entire planets.
Zombie
Zombies are the core mechanic of the special plague known as the Necroa Virus. They are the undead hosts of the Necroa Virus, created from reanimated humans. Zombies crave only to consume the remaining living human population wherever they may be.